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Low dose conference held in Berlin on Sept 11 – 13th 2012

WECF along with a number of other NGOs participated in the low dose conference “From theory to practice” in Berlin, organised by NIEHS.

25.09.2012 |WECF

At the low dose conference, scientists, doctors, and NGOs were discussing about  the risks of Endocrine Disrupting Chemicals (EDCs) in the everyday environment. Although already low doses have negative health effects, the OECD measure guidelines are set at too high levels.

Within the EU and other OECD countries, toxicity levels are set very high, at the level of a poisoning. Therefore, the testing practices in place often do not consider the effects of low doses of exposure to chemicals. especially EDCs have the ability to disrupt the human hormone system in low doses, but might not do so in high doses. Hence, with the high toxicity levels, the health risks of EDCs are simply overlooked and ignored. especially pregnant women and young children are at risk of EDCs, as WECF educates on the Nesting Project website.

Using a new on-the-spot-voting tool, one of this conferences conclusions by a vast majority (90%) of the participants was that there is such a thing as a low dose effect. It was demonstrated that non-monotonic low dose response curves do exist. This means that effects of exposure to low doses does affect the body, but not at very high doses which would be considered to cause poisoning. However, participants also agreed that current OECD standards were too constraining, for instance in cost and reproducibility demands, to allow for testing for low dose effects.

On the second and third day, workshops focused on suggestions for improving risk assessment. Strategies named were to test and assess risks by starting with tests based on computer models, moving to extensive in vitro (live cell-cultures) testing. After this, if necessary, testing on live animals could be pursued.

See for more information on the conference here.

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